Common sleep aid may disrupt system that clears brain waste linked to Alzheimer's
Researchers have discovered that certain over-the-counter sleep aids, particularly those containing antihistamines like diphenhydramine, may interfere with the brain's glymphatic system.
This system is responsible for clearing out waste products, including beta-amyloid proteins, which are associated with Alzheimer’s disease.
The glymphatic system is most active during deep sleep, working to flush out toxins that accumulate during the day.
However, antihistamines can alter sleep patterns and reduce the time spent in restorative deep sleep, potentially hindering the system's efficiency.
Long-term use of these sleep aids could contribute to the buildup of harmful proteins in the brain, increasing the risk of cognitive decline and neurodegenerative diseases.
Experts recommend exploring alternative methods for improving sleep, such as maintaining a consistent sleep schedule, reducing caffeine intake, and practicing relaxation techniques before bed.
While occasional use of sleep aids may be harmless, their regular use warrants caution. Further studies are needed to understand the full impact of these medications on brain health and Alzheimer's risk.